Might as well face it, you're addicted to MYC
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چکیده
منابع مشابه
Might as well face it: MLL's addicted to HOX.
Chromosomal rearrangements involving the MLL gene are a characteristic feature of a variety of human leukemias, including acute lymphoid (ALL) and acute myeloid leukemias (AML) as well as secondary leukemias resulting from treatment with topoisomerase inhibitors.1 The MEIS1 and HOXA9 genes have been shown to be major downstream targets of MLL fusion proteins.2 The mammalian HOX genes encode DNA...
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ژورنال
عنوان ژورنال: Nature Reviews Cancer
سال: 2010
ISSN: 1474-175X,1474-1768
DOI: 10.1038/nrc2908